Fibrosis相关论文
目的 探讨特发性肺纤维化(idiopathic pulmonary fibrosis,IPF)患者患病的真实体验及其护理需求.方法 采用面对面半结构式访谈收集......
目的:探讨C-X-C趋化因子受体4(CXCR4)在小鼠草酸钙晶体致肾损害和纤维化中的作用和机制。方法:2021年6月将15只雄性C57/BL6小鼠按......
Glutaminolysis-ammonia-urea Cycle Axis, Non-alcoholic Fatty Liver Disease Progression and Developmen
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide, reflecting the current epidemics of......
Redefinition of Fatty Liver Disease from NAFLD to MAFLD through the Lens of Drug Development and Reg
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) affects a third of the population and is a leading cause ......
目的:探讨mTOR/HIF-1α信号通路在布-加综合征(B-CS)肝纤维化中的作用机制。方法:雄性C57小鼠20只按随机数字表法分为假手术(Sham)......
特发性肺纤维化(IPF)是一种慢性、进行性且最终致命的肺纤维化疾病，其病理特征包括肌成纤维细胞的积累和肺组织中细胞外基质沉积的......
The excess deposition of underlying extracellular matrix(ECM)in adipose tissue is defined as adipose tissue fibrosis tha......
Activation of Silent Information Regulator 6 Signaling Attenuates Myocardial Fibrosis by Reducing TG
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慢性乙型肝炎患者抗病毒治疗后低病毒血症逐渐引起重视，其与肝纤维化进展、肝细胞癌发生和长期生存率降低相关。作为疾病进展的危险......
Fibrosis is a condition in which connective tissue replaces normal parenchymal tissue,resulting in significant tissue re......
目的:探究n 68Ga-1，4，7，10-四氮杂环十二烷-1，4，7，10-四乙酸(DOTA)-成纤维细胞激活蛋白抑制剂(FAPI)-04 PET/CT在评估不同病理分级......
Myelin-associated glycoprotein combined with chitin conduit inhibits painful neuroma formation after
Studies have shown that myelin-associated glycoprotein(MAG)can inhibit axon regeneration after nerve injury.However,the ......
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Objective: To evaluate the preventive effect of salvianolate (Sal B) onglucose metabolism disorders of dimethylnitrosami......
Early intervention with Di-Dang Decoction prevents macrovascular fibrosis in diabetic rats by regula
Macroangiopathy is a complication of Type Ⅱ Diabetes Mellitus (T2DM),which is mainly caused by fibrosis of blood vessel......
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress
Previous studies have shown that oxidative stress and corporal fibrosis in penile tissues of rats were key pathological ......
Role of inhibiting LIM-kinase2 in improving erectile function through suppression of corporal fibros
We evaluated whether LIM-kinase 2 inhibitor (LIMK2i) could improve erectile function by suppressing corporal fibrosis th......
Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of
The aim of this study was to investigate the mechanism by which a diet inducing high hyperhomocysteinemia (HHcy) leads t......
Losartan improves erectile function through suppression of corporal apoptosis and oxidative stress i
This study aimed to investigate the functional and morphological changes in the corpus cavernosum after cavernous nerve ......
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Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived f
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The effect of miR-145 inhibits chondrocyte proliferation and fibrosis by targeting TNFRSF11B in huma
Objective:Osteoarthritis (OA) is a common cause of functional deterioration in older adults, altered chondrogenesis is t......
amplified caseous necrosis and perinecrotic fibroplasia in granuloma of tuberculosis with diabetic c
Objectives:To compare the thin-slice CT features of two groups of age- and gender-matched TB patients with (DM-TB) or wi......
Purpose Pulmonary fibrosis is characterized by an extensive activation of fibrogenic cells and deposition of extracellul......
Anti-inflammation and Anti-oxidation of Ascorbic Acid Increases Multifidus Muscles Healing and Reduc
Objectives:To attenuate oxidative stress damage and inflammation of the multifidus muscles after posterior lumbar surger......
IL-17A contributes to postoperative atrial fibrillation by regulating inflammation and fibrosis in s
Background/Aims:Postoperative atrial fibrillation (AF) remains a common cause of morbidity.Increasing evidence indicates......
Intravenously injection of silica nanoparticles induces liver injury in mice and related mechanism s
As Silica nanoparticles (SiNPs) have been widely used in the biomedical and pharmaceutical fields, the adverse effects a......
The inhibition effect of salvia miltiorrhiza on collagen synthesis in rats after sciatic nerve injur
Summary To investigate the inhibition effect and mechanism of salvia miltiorrhiza on the muscular fibrosis in the rat af......
Galectin-3(Gal-3)is a member of a β-galactoside binding lectin family.It is involved in numerous physiological and path......
Combination with MSCs and ACE2 is Superior for Amelioration of Mesangial Cell Fibrosis and Oxidative
Aims: Mesenchymal stem cells(MSCs)have beneficial effects in diabetic nephropathy(DN),can also serve as vehicle for gene......
Background:Anti-VEGF therapy (intravitreous bevacizumab) is a rational approach to treating retinal or choroidal neovasc......
Interleukin-12p35 Deletion Promotes CD4 T-Cell-Dependent Macrophage Differentiation and Enhances Ang
Objective Interleukin-12 is essential for the differentiation of na(i)ve T cells into interferon-γ-producing T cells, w......
High glucose-induced Inflammatory response and Fibrosis of human mesangial cells via Rho/ROCK signal
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Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist inhibits collagen synthesis in human h
The transcription factor peroxisome proliferator-activated receptor-γ (PPAR-γ)functions to regulate cell differentiati......
Metformin attenuates angiotensin Ⅱ induced cardiac fibrosis and transforming growth factor-β1 produc
Aim In diabetic patients, mefformin appears to provide cardiovascular protection that cannot be attributed only to its a......
Angiotensin Ⅱ(AngⅡ)plays an important role in the pathogenesis of hypertension and associated renal injuries.To elucid......
The toxic mechanism of silica nanoparticles(SiNPs) on liver which is the main scavenger for blood borne xenobiotics stil......
Background: The hypertrophic scar (HS) is a serious fibrotic skin condition and a major clinical problem.Interleukin-10 ......
The transforming growth factor (TGF)-β/Smad signal transduction pathway is closely associated with hypertrophic scar (H......
Objective: This study is designed to investigate whether the Müller glial cells in diabetic retinopathy participates in......
The Relationship between Anti-Vascular Endothelial Growth Factor and Fibrosis in Proliferative Retin
Purpose To investigate the progression of retinal fibrosis after intravitreal bevacizumab injection(IVB)therapy in patie......
Skin scarring, tightly associated with fibrosis, is a wound-healing by which the body attempts to repair itself followin......
Expression,purification,and characterization of a neovasculature targeted rhIL-10 in Escherichia col
Interleukin 10 (IL-10) is a pleiortropic cytokine which plays a pivotal role in the inflammatory response, immunological......
Matrine inhibits infiltration of the inflammatory Gr1hi monocyte subset in injured mouse liver throu
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Taurine supplementation improves erectile function in rats with streptozotocin-induced type 1 diabet
Objective: For patients with diabetes,erectile dysfunction (ED) is common and greatly affects quality of life.However,th......
